IN VIVO LINEAGE TRACING REVEALS AXIN2-EXPRESSING, LONG-LIVED CORTICAL THYMIC EPITHELIAL PROGENITORS IN THE POSTNATAL THYMUS.

In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus.

In the thymus, cortical and medullary thymic epithelial cells (TECs) are instrumental for generating a repertoire of functional T cells.Hence, there has been much interest in the ontogeny of TECs.While medullary TEC (mTEC) and bipotent progenitors have been identified, the existence of a cortical TEC (cTEC) Commercial Product (Sanitization) progeni

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Task-dependent inhibition of slow-twitch soleus and excitation of fast-twitch gastrocnemius do not require high movement speed and velocity-dependent sensory feedback

Although individual heads of triceps surae, soleus (SO) and medial gastrocnemius (MG) muscles, are often considered close functional synergists, previous studies have shown distinct activity patterns between them in some motor behaviors.The goal of this study was to test two hypotheses explaining inhibition of slow SO with respect to fast MG: (1) i

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Correlation of Antagonistic Regulation of leuO transcription with the cellular levels of BglJ-RcsB and LeuO in Escherichia coli

LeuO is a conserved and pleiotropic transcription regulator, antagonist of the nucleoid-associated silencer protein H-NS, and important for pathogenicity and multidrug resistance in Enterobacteriaceae.Regulation of transcription of the leuO gene is complex.It is silenced by H-NS and its paralogue StpA, and it is autoregulated.In addition, in Escher

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Poststroke neuroplasticity processes

The paper considers different aspects of neuroplasticity in patients with stroke.It underlines the dynamism of this process and the ambiguity of involvement of the structures of the contralateral cerebral hemisphere in the restorative process.It considers the periods after onset of stroke and the activation of different brain regions (of both the i

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